ethyl beta-alaninate hydrochloride
beta-Alanine ethyl ester hydrochloride
CAS: 4244-84-2
Molecular Formula: C5H12ClNO2
ethyl beta-alaninate hydrochloride - Names and Identifiers
ethyl beta-alaninate hydrochloride - Physico-chemical Properties
| Molecular Formula | C5H12ClNO2 |
| Molar Mass | 153.61 |
| Melting Point | 67-70°C(lit.) |
| Boling Point | 167.8°C at 760 mmHg |
| Flash Point | 41.4°C |
| Water Solubility | almost transparency |
| Vapor Presure | 1.67mmHg at 25°C |
| Appearance | White to white-like crystals |
| Color | White to off-white |
| BRN | 3559095 |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Sensitive | Hygroscopic |
| MDL | MFCD00012909 |
ethyl beta-alaninate hydrochloride - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S22 - Do not breathe dust. S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29224995 |
| Hazard Class | HYGROSCOPIC |
ethyl beta-alaninate hydrochloride - Reference Information
| Use | Beta-alanine ethyl ester hydrochloride is a β-alanine ester compound. β-alanine ester is an important amino acid derivative, which has important applications in the preparation of pharmaceutical and pesticide intermediates. |
| preparation | add 200g of ethyl cyanoacetate, 2000g of ethanol, 40g of sodium hydroxide and 40g of Raney nickel to the reaction vessel, seal the reaction vessel, replace it with nitrogen for three times, replace it with hydrogen for three times, then fill it with hydrogen until the pressure is 8Mpa, raise the temperature to 70 ℃, stir for 10 hours, and continuously supplement hydrogen to maintain the pressure of 8Mpa during the reaction, until the reaction pressure does not change, the reaction is over, the catalyst is filtered out, the filtrate is concentrated to colloid under reduced pressure, 200g of methanol is added, the methanol solution of hydrogen chloride is added dropwise under cooling condition, the dropwise addition is stopped until the pH is 3, the system is concentrated to half, the solid is precipitated, the mixture is dried to get 158g of beta-alanine ethyl ester hydrochloride, the purity is measured to be 98.6%, and the concentration is continued to get 100g of beta-alanine ethyl ester hydrochloride, the purity was measured to be 98.6%, and the conversion rate of methyl cyanoacetate was calculated to be 95.0%. |
Last Update：2024-04-09 19:05:12
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Spot supply
Product Name: β-Alanine ethyl ester HCl Visit Supplier Webpage Request for quotationCAS: 4244-84-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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